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Since low levels of CCTα lead to abnormalities of cilia tips (Figure 2L and M) and mutant cells also have abnormal tips we decided to investigate if the mutated form of CCTα was targeted to cilia.
In other words, although minor subcortical deficits associated with tinnitus may cause abnormal inhibition of ASR (Fournier & Hébert 2013), these do not lead to abnormalities in the detection of gaps as used in the current paper.
Aberrant protein isoforms can lead to abnormalities in protein function and may even result in genetic disorders or cancer.
Perhaps they are a presage to Seralini et al. indicating that some features of rat chow can lead to abnormalities in sensitive animals.
Shortening through compression might lead to abnormalities at the wrist (creating an ulna minus or ulna plus), needing a secondary shortening or lengthening operation.
At a dimensional level, childhood trauma may lead to abnormalities in affect regulation, impulse control and cognitive functioning that could reduce the ability to cope with later environmental risk factors (cannabis misuse, stressful life events).
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Genome instability could lead to abnormality of nuclear structure, while excessive protein aggregation could cause ER malfunction.
There is abnormal vacuolization in cells of mesenchymal origin, especially fibroblasts, which leads to abnormalities in connective tissues.
Their experts (one of whom spoke at the committee hearing today) gave their assessment of what they say 'may' have led to abnormalities in my data.
This leads to abnormalities in protein production (identified by deranged coagulation) and metabolism by the liver.
The failure of regulation of apoptosis leads to abnormalities such as developmental defects, cancer, autoimmune diseases, and neurodegeneration [2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com