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Thus, enhanced neuronal classical MHCI expression can lead to aberrations in neural circuitry and neurorepair.
These gain- and loss-of-function mutations lead to aberrations in protein-protein interaction networks.
An understanding at this level, however, is critical for eventual resolution of the mechanisms that underlie cell fate decisions, as well as those that lead to aberrations in cellular behavior [ 10].
Combined with the results in ovarian cancer cells, it appears that manipulation of Rab25 levels can lead to aberrations in the trafficking of β1-integrin and perhaps other critical regulators of cell adhesion.
From a biological point of view this may not be favorable because gene pattern defects can lead to aberrations in development, hence development should be robust towards modest transient disturbances [ 53, 54].
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We expect this technique to lead to aberration correction and improved resolution [ 7, 8].
As expected, injecting embryos with MO2 (0.5–1 mM) markedly reduced viability and led to aberrations in body axis development and pericardial edema in a fashion similar to the ATG-targeted Pak1 MO1 (Fig. S3B).
During the heating steps, bubble formation in the PCR chambers led to aberrations in the course of amplification as exemplarily shown in cycle 20 and 39 of sample 2 (see Fig. 4a).
This leads to aberration and scattering of the ultrasonic waves.
The case control design was, however, based on a hypothesis that exercise cannot lead to chromosome aberrations in the fetus, as the control group consisted of women with miscarriages with chromosome aberrations.
Such a phenomenon may lead to mutational aberrations in the recipient cells and enhance the probability of wound carcinogenesis.
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