Sentence examples for lead to a rugged from inspiring English sources

Epistasis can also constrain the end point of an evolutionary trajectory, as it can lead to a rugged fitness landscape containing many local minima into which evolving species can become trapped.

Structural characterization suggested more defects formed on the NCNTs synthesized from ferrocene (Fc-NCNTs) which led to a rugged surface morphology compared to the NCNTs synthesized from iron II) phthalocyanine (FePc-NCNTs).

Such frustrated folding leads to a rugged free energy landscape in vitro, featuring multiple local and global minima that can represent either functionally active or inactive states [12] [16].

The non-linearity of the relationships between the two factors and overall performance leads to a rugged 'performance landscape' with hills, ridges and valleys representing respectively better performance, knife-edge performance and worse performance for particular combinations of the two factors [ 19].

For example, a heterogeneous environment might lead to a more rugged adaptive landscape, making it more likely that replicate populations would evolve toward distinct adaptive peaks, relative to a uniform environment.

This leads to a completely rugged landscape, where a single mutation changes the fitness effects of all other possible mutations.

Brahms's C-Minor Quartet, in the hands of the Catalyst Quartet, rose to a rugged finish.

There is some evidence that women are more susceptible than men, very young children more than adults, those who lead sedentary, indoor lives more than those who lead a rugged life of work or exercise in the open.

When you mix that attitude with a rugged outdoors culture of booze and fighting, you're basically creating huge muscular toddlers whose tantrums can lead to broken noses.

By Soulcalibur IV, Astaroth's appearance was completely changed, altered to resemble a "rugged rocky" golem.

But this is only a first step in what needs to be a rugged climb.