Sentence examples for lead to a perturbation from inspiring English sources

Figure 8A shows how a possible interaction between the Wnt signalling pathway, Regulation of Actin Cytoskeleton (linked to PCFs) and Focal Adhesion (predictive of toxicity outcome) could lead to a perturbation of actin cytoskeleton polymerization.

The resulting intracellular influx and accumulation of sodium and chloride lead to a perturbation of calcium homeostasis and to cell swelling [ 61, 62].

Also, by examining the eQTL hotspot regions in the genome, these studies identified candidate regulators whose genetic variations lead to a perturbation of the gene cluster's gene expression levels.

Culling of badgers may result in more dispersal of individuals, with the potential to lead to a perturbation effect (higher bTB as a consequence of disruption to the badger social system due to badger culling [ 48, 49]).

Any perturbation on the radiation model leads to a perturbation on the velocity identified by the inversion process.

Since FTY720 leads to a perturbation of S1P signaling, its use as an immunosuppressant could have an impact on articular cartilage.

Nevertheless, substituting the wheat cytoplasm with the H. chilense cytoplasm led to a perturbation of the central metabolism in response to high light (HL), resulting in a separation of the euplasmic control from the H. chilense alloplasmic line with the PCA not observed under low light (LL).

In addition, knockdown of SUCLG2 in SUCLA2-deficient fibroblasts reportedly results in mtDNA depletion and reduction in NDPK activity (Miller et al., 2011), suggesting that disruption of a SCS-NDPK complex leads to a perturbation of mitochondrial nucleotide (dNTP) pools that affects mtDNA replication.

A naive use would thus lead to a very dense perturbation graph (in the extreme case, all nodes are connected to each other), which essentially contains only little meaningful wiring information of the real graph.

Nevertheless, it is clear from this analysis that centrosome amplification does not lead to a large-scale perturbation of the transcriptome and that only a relatively small number of genes, if any, are consistently mis-regulated in cells as a result of centrosome amplification.

Slow variation of the cable length leads to a singular perturbation problem which is expressed in slowly changing, time-dependent coefficients in the governing differential equation.