Exact(1)
When aPKC ι-Par6 complexes were decreased, increased free aPKC ι and blocked downstream signal transduction would lead to a downregulated expression of aPKC ι by reactively regulating the translation and the expression.
Similar(59)
Further Tm treatment lead to a significant change in the expression of 38 (16 upregulated and 22 downregulated) miRNAs.
We found that Tg treatment lead to a significant change in the expression of 48 (23 upregulated and 25 downregulated) miRNAs.
Impaired RNA processing may directly lead to a reduction in mature mRNA; therefore, we focused on genes that were downregulated by Cdc5L knockdown.
Both are downregulated in bony metastases arising from prostate cancer, and transfection into PC3 cells has been shown to lead to a more epithelial phenotype in vitro, with increased E-cadherin and reduced fibronectin expression [ 34].
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