Thus, vaccination does not reinforce the in vivo selection that occurred during chronic infection but leads to a diversification of the VZV-reactive T cell repertoire.
These acquisitions the company's primary business strategy–have led to a diversification of products and customers, and protect it against regional and industry-specific economic volatility.
Stricter border controls to prevent irregular migration from Africa to Europe, for example, have not stopped migration flows but instead led to a diversification of migration routes and to a much more dangerous migration journey (de Haas 2009).
The development of recent technologies has led to a diversification of products.
Such evolutionary events are thought to be the biological basis of the immense plasticity of Brassica species and may have led to a diversification of the genes retained in more than one copy, in terms of function and/or expression.
The second wave of duplication is vertebrate-specific and leads to a diversification inside the subfamilies, with the emergence of the presently known isotypes such as PPAR α, PPAR β, and PPAR γ [ 3, 7].
Attempts to remedy potential biases present in traditional peer review have led to a diversification of peer review practices, for instance through the use of author-blind and non-selective review, the removal of traditional reviewer anonymity, and the introduction of various forms of community review.
The rapid urbanization process in Pune has an impact on urban health in various ways: high population densities, environmental and infrastructural degradation, unequal access to health care, and strong social stratification and fragmentation, as observable in many cities in low- and middle-income countries, jeopardize improvements in disease control and lead to an epidemiological diversification.
Furthermore, socio-economic cost factors such as labor costs, which are specific for each respective country, lead to a strong spatial diversification.
On the other hand, the inability of some stefins to efficiently inhibit particular cathepsins may have led to a functional diversification, which resulted in a varying specificity of stefins produced by a single species.
