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The structure of the e-commerce system is complex [1] and providing users with a large amount of commodity information can lead to a bottleneck.
Electrical double layer supercapacitors (EDLC) have an upper limit for their area-normalized capacitance (CA) and lead to a bottleneck that impede the commercialization of high-energy-density supercapacitor devices.
These difficulties lead to a bottleneck for us to achieve novel or better therapeutics with the one-drug-one-target paradigm.
Excessive hospital occupancy can lead to a bottleneck effect in which completely occupied floor beds prohibit transfers out of the ICU and thus prohibit the admission of critically ill surgical patients into the ICU.
Similar(55)
We hypothesized that this phenomenon is due to increased protein synthetic flux, causing folding stress that leads to a bottleneck in the protein secretion pathway.
The success of genomics has led to a bottleneck in target validation that could be overcome by using small diverse organic compounds to interfere with biological processes.
In low resource settings, the dearth of available experts to assess therapy quality potentially leads to a bottleneck in scaling up lay therapist delivered psychological treatments.
The latter is more likely when turnover leads to a bottleneck, which reduces effective population size (Ne) and accelerates genetic drift with different alleles being lost from each population.
Occasionally over the last decade, when filibuster overuse led to a bottlenecking of nominees awaiting confirmation votes, the majority has threatened majority-vote changes to the rules to weaken the filibuster.
The candidate gene approach was based on the prior knowledge about functional aspects of possible candidates, which may lead to an information bottleneck.
He says that broker dealer capacity to handle rapid shifts in portfolios is actually smaller than pre-2008, and could lead to a massive liquidity bottleneck.
Related(17)
lead to a setback
lead to a constriction
lead to a challenge
lead to a shortage
lead to a shortcoming
lead to a block
lead to a stalemate
lead to a cap
lead to a difficulty
lead to a backlog
lead to a vulnerability
lead to a limitation
lead to a standoff
lead to a size
lead to a jam
lead to a problem
lead to a blockage
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com