Sentence examples for lead substance from inspiring English sources

These probes consist of a fluorophore with excitation and emission in the NIR such as Cy 5.5 and an affinity ligand such as an antibody, an antibody fragment, a peptide, or a nonpeptidic lead substance.

The aim of the following study, therefore, was to further elucidate interactions between the coagulation and inflammatory system in the microvasculature using AT as lead substance due to its influence on both systems and to further evaluate which of AT's active profiles are crucial for the anticoagulant effectiveness.

Therefore, the present data provide a novel approach and specify a lead substance for the development of drugs that induce apoptosis independently of Bax and Bak.

Next to its anticancer effect in single-agent treatment, pretubulysin strongly sensitizes to TRAIL-induced apoptosis, and thus broadens its therapeutic potential as a lead substance for novel antimitotic drugs in treatment of metastatic cancer.

More than 2000 compounds were virtually screened and as a result 114 virtual lead substances were selected for subsequent experimental verification.

As the former Chief of Addiction Medicine at Rikers Island jail complex, I led substance use treatment and recovery services in one of the nation's largest addiction facilities.

Such has repeatedly been the case with children's exposure to lead, a substance known since 1923 to damage the brain.

"A life on the streets can lead to substance misuse, crime and serious physical or mental health problems".

Future research may wish to consider ethnographic studies of this time period to better identify what conditions lead to substance use in a post-release population.

In the later stages, lead drug substance and drug product formulations are evaluated for freeze-thaw stability to verify the formulation robustness.

Just as mental health issues often lead to substance abuse, a lack of physical exercise or nutrition can also lead to depressive mood states and a lack of focus.