Motor neurons normally express Ca2+-impermeable AMPA receptors containing GluA2 with arginine residue at the Q/R site (GluA2R) in the assembly, but express Ca2+-permeable AMPA receptors when GluA2Q is expressed, which leads motor neurons to death.
She had vowed to lead a motor procession some 310 miles over two days beginning Saturday, from Lahore to the northwestern town of Peshawar.
Most of the methods utilized for cogging torque reduction lead to motor structure complexity, increasing manufacturing cost and also influencing the output torque.
ALS can lead to motor disability so severe that the patient enters the "locked-in" syndrome.
23 25 Sleep apnoeas, in turn, may lead to motor vehicle crashes, hypertension, heart failure, arrhythmias, cardiovascular diseases and death.
Neurological deficits caused by H-I (hypoxia-ischaemia) to the perinatal brain are often severely debilitating and lead to motor impairment, intellectual disability and seizures.
This allows us to test the hypothesis that disruptions in functional connectivity lead to motor weakness in patients with brain tumours.
Clear description of how functional connectivity deficits lead to motor weakness is needed to establish the use of resting functional MRI as a clinical tool for surgical planning.
Cerebellar defects in FA patients lead to motor coordination difficulties, and the level beam test mimics the walking score in the FARS ataxia score (47).
Together, these data suggest that the loss of C9orf72 protein can lead to motor abnormalities, which argues for a role of loss of function in C9FTD/ALS.
