Sentence examples for lead for development from inspiring English sources

This compound is one of the most potent non-secosteroidal VDR agonists reported to date, and is a promising lead for development of novel drug candidates.

These results suggest that the compounds can be taken as lead for development of new drugs for the treatment of immune related inflammatory disorders, such as cancer and rheumatoid arthritis.

Additional safety evaluation (no blood pressure elevation in guinea pigs) and pharmacokinetics studies indicated that the potential druggability for compound 20 which is a promising lead for development of a new class of CETP inhibitors for the treatment of dyslipidemia.

These compounds may be used as a lead for development of new antioxidant agents.

Thus, 41 may serve as a promising new lead for development of anti-AIDS clinical trial candidates.

The compound 2t represents a promising new lead for development of novel therapeutic agents for treatment of androgen-independent prostate cancer.

The results suggest that the synthesised substituted quinolines are promising leads for development of new drug to treat TB.

Peptides derived from larger molecules that are important modulators in cancer regression are becoming leads for development of therapeutic drugs.

Together, these novel benzimidazole derivatives may possess potential as leads for development of effective anti-inflammatory drugs with multi-target properties for dually inhibiting LT and PGE2 production.

Together, these diaryl-isoxazol-3-carboxylic acids may possess potential as leads for development of effective anti-inflammatory drugs through inhibition of LT biosynthesis.

The inhibition of Mycobacterium tuberculosis at concentrations as low as 1.6 and 1.5 μg/mL by compounds 5f and 7d respectively indicates that these compounds can act as leads for development of newer anti-TB compounds.