Sentence examples for lcrs 1 from inspiring English sources

KD has seven loops protruding from the core fold into two largely opposite directions, dubbed loop cluster regions (LCRs) 1 and 2. Mutational analysis of previously isolated agonistic KD variants against human death receptors (DRs) 4 and 5 revealed that they can simultaneously recognize two target molecules of DR4 and/or DR5 via the two independent binding sites of LCR1 and LCR2.

Surprisingly, we found that many deletion breakpoints occurred in low-copy repeats (LCRs); 13 were associated with novel large LCR17p structures, and 2 mapped within an LCR sequence (middle SMS-REP) within the Smith-Magenis syndrome (SMS) common deletion.

Although proximal breakpoints were highly variable, distal breakpoints tended to cluster around low-copy repeats (LCRs) (50% of distal breakpoints), and each duplication event appeared to be unique (100 kb to 4.6 Mb in size).

It has been estimated that the 5% of the human genome is constituted by segmental duplications or Low Copy Repeats (LCRs) [1].

This region contains eight chromosome 22-specific LCRs (LCR22s; LCR22-A to LCR22-H).

This will affect the LCRs, Cai2+ transients and all Cai2+-dependent currents including ICa, L

Typically, the NAHR breakpoints are located in LCRs 10 to 300 kb in size that share over 95% similarity [ 14].

PCR-based techniques have also allowed the quantification of the number of repeats shaping specific LCRs (7q11.23; [9]).

HCRs spent more time in the running wheel than LCRs (2.6-fold; P<0.001), which explained most of the difference in the running distance (r=0.96; P<0.001).

Consistent with this result, it has been demonstrated that HCRs have enhanced capacity for hepatic and skeletal muscle oxidation of lipids relative to LCRs (30, 31).

The percentage of species-specific LCRs that mapped to regions with more than 50% of gaps in all other species was 74.3% for human-specific LCRs, 75.7% for mouse-specific LCRs, 46% for chicken-specific LCRs, 39% for zebrafish-specific LCRs and 34% for C.intestinalis-specific LCRs.