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Under the OLC paradigm, the computational time for assembling more reads rises exponentially with data complexity because the number of pairwise comparisons to detect overlaps will increase, and the layout graphs will be harder to resolve into a consensus sequence.
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First, hierarchical layout hypergraphs (HL-graphs) representing designs and hierarchical layout graph grammars generating them are specified.
Section 3 develops a graph-theoretical model for a rectangular floor plan which is called building layout graph (BLG).
After N - 1 iterations, where N is the order of the building layout graph, the complete MST is found.
Nodes (or Vertices): The wall-wall-floor trihedrals inside the building are treated as nodes of the building layout graph.
The building layout graph (BLG) model is firstly established using the wall-wall-floor trihedrals inside the building.
The node set, edge set, and other nomenclatures are defined as follows: (i) Nodes (or Vertices): The wall-wall-floor trihedrals inside the building are treated as nodes of the building layout graph.
CIRCOS is originally designed for visualization of genomic data in the form of circular layout (graph) and hence the configuration and data files represent data in context of chromosome positions.
Note that the resulting layout graph is not necessarily connected.
The algorithm to generate the layout graph is formally described in Figure 3.
The layout graph can be analyzed to make assumptions about repeating contigs and rearrangements.
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