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Apoptotic cells were detected in 1.5-month-old Ifnb –/– granular layers of olfactory bulbs, the granular dentate gyrus of hippocampus and the subventricular zone, and the striatum (STR) caudate putamen including the ependymal cell layer in 12-month-old Ifnb –/– mice, but not detected in Ifnb +/+ sagittal brain sections at similar ages.
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We observed high AVTr expression in granular cell formations in the internal cellular layer of olfactory bulbs, torus longitudinalis, granular layer of the corpus cerebellum, valvula of the cerebellum, nuclei of the lateral and posterior recesses, and granular eminence.
The mammalian homologue of Kin5, Kif17, is endogenously expressed in the ciliary layer of olfactory neurons and in MDCK cell cilia.
Sections containing the periglomerular cell layer of olfactory bulb were mounted directly on membrane slides for LMD and immediately processed by alcohol dehydration/fixation. Leaving mounted sections even at −70°C was found to impair tissue morphology.
Note that instead of the convolutions of the adult olfactory lamellae, there is a single layer of olfactory epithelium covering the olfactory wall in the larval lamprey that also expresses Golf α and 6425.OR330a.
At E12.5 and E14.5, Chd7 protein was present in all layers of the olfactory epithelium and olfactory bulb.
Marked atrophy of the olfactory nerve and glomerular layers of the olfactory bulb was also detectable by 7 days PI along with mild neutrophilic encephalitis.
Responses of interneurons were recorded in deep layers of the olfactory bulb that contain predominantly granule cells.
Mature granule and periglomerular cells were recognized by their morphology and their position in different layers of the olfactory bulb.
Somata of interneurons in the deeper layers of the olfactory bulb are densely packed and show pronounced Ca2+ signals in response to odor stimulation (Fig. 10A) [35], [35].
Luskin et al. (1993) observed neuroprogenitor cells arising in the SVZ appearing as interneurons in the glomerular and periglomerular layers of the olfactory bulb (OB) and hypothesized that there exists a route connecting the two areas [25].
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