The YFP staining pattern in cerebellum suggested cre-mediated recombination restricted to neurons of the granular and molecular layers without involvement of purkinje cells.
After injections in V1, V4, and TEO areas, neurons were detected preferentially in several feedback pathways but, unusually, were restricted to deeper layers without involvement of layers 2 or 3. Temporal injections resulted in more extensive labeling of both feedback and intratemporal association pathways.
It has been reported that Hes1, which is expressed in the spinous layers, mediates spinous gene induction but not repression of basal layer genes, raising the possibility of involvement of other Hes/Hey family genes [ 21 ].
In all cases, the uptake zone was characterized with respect to the retinotopic representation of the area injected, sampling of cortical layers, and possible involvement of white matter.
For the cultures established with the 1119 Ficoll layer, the involvement of progenitors or precursors of the erythroid lineage was assumed because postculture sorting was directed toward cells expressing the erythropoietin receptor.
Aortic dissection typically produced a large pseudo-lumen filled with extravasated blood, with clear evidence of involvement of the medial and adventitial layers.
20 The Dukes staging system (used for colon cancer staging originally) was defined as follows: (A) tumor in the mucosa, (B) tumor in the muscle layer, (C) involvement of lymph nodes, and (D) distant metastases.
Despite some articles suggesting the involvement of two layers of the vessel's wall, we believe that structural changes are based mainly on the adventitia, thus explaining the eccentric growth of the lesion.
The growing number of helicases implicated in the maintenance of genomic stability and shown to unwind G4 nucleic acids suggests multiple layers of complexity in terms of helicase involvement.
These latter originate from neurons in the deeper layers, with some involvement of layers 2 and uppermost 3 (Rockland and Pandya 1979; Felleman and Van Essen 1991).
