Sentence examples for lay significant from inspiring English sources

Present study describes a detailed GQSAR analysis on 1,4-dihydropyridine (DHP) derivatives, reported as potential inhibitors of BACE-1 [ 4], in order to elucidate the structural features of the molecular fragments of these molecules that lay significant contribution towards their biological activity.

Beneath those top-line numbers, however, lie significant gender-based disparities in voting.

Behind the shift -- besides sheer exasperation with decades of policy immobility -- lie significant changes in the strategic environment.

Their fathers both military officers were close friends.But behind the human interest story lie significant ideological differences.

Behind the positive global trends, however, lie significant differences among and within countries.

Yet behind the confident public pronouncements about the value of torture lay a significant body of evidence casting doubt on it.

Are we leaping to an unjustified conclusion when we lay a significant part of the blame for obesity, chronic disease and the dramatic rise in reported food allergies at the door of processed food?

Mr. Dimon said he did not anticipate having to lay off significant numbers of the bank's 82,500 employees, nor did he intend to sell the credit card business or Wingspan.com, an Internet-based bank.

While Democrats will be hiring more employees as they take charge of the Senate's $95 million budget, Republicans will almost certainly be forced to eliminate positions and lay off significant portions of their staffs.

Profits fell sharply and in 2011 it was forced to lay off significant numbers of its car sales staff.

Outcrossed females from male female populations at (G100) may lay a significant higher number of embryos before day 4 than their ancestrals (t149.7 = 1.8, p = 0.08), but not after day 4.