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laxation
noun
The act of loosening or slackening, or the state of being loosened or slackened.
synonyms
Exact(57)
Patients will report its effect in a laxation diary.
The median time to laxation was approximately 30 minutes after administration of methylnaltrexone.
No laxation response was observed in the 11 patients receiving placebo.
Neither study was designed to assess the impacts of daily laxation treatment.
Those patients treated by conventional means eventually produced laxation after a further 3 to 5 days.
Subsequent doses could be increased to 0.30 mg/kg if no laxation occurred within 4 hours.
One patient did not respond due to faecal impaction but subsequently experienced laxation after manual disimpaction.
(GP3) There were worries about colonoscopy and laxation being trying for the patients.
Patients will be asked to complete the laxation diary and BFI according to the study schedule.
The primary efficacy endpoints were laxation within 4 hours after a single dose of the study drug.
Methyl-naltrexone was administered to seven patients at 0.15 μg/kg subcutaneously on alternate days until laxation occurred.
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