Secondary aims were to investigate the relative contributions of the side of biopsy (hemiplegic or contra-lateral), baseline 25 hydroxyvitamin D (25OHD), stroke severity and functional status to changes in bone remodelling in stroke patients.
Baseline lateral femur CDI, baseline lateral tibia CDI, and baseline lateral tibiofemoral CDI are associated with both lateral JSW and static alignment (see Table 2 and Supplementary Figures 1 and 2 in Supplementary Material available online at http://dx.doi.org/10.1155/2015/634275).org/10.1155/2015/634275
Furthermore, the reduction of the augmented ridge width right after the lateral augmentation (baseline) to implant placement (after 4 months) was assessed in each subjects.
Intratester (ICC (3, 1 model)) reliability for baseline lateral femur, lateral tibia, and total lateral tibiofemoral ranged from 0.86 to 0.98.
We found a good correlation between baseline lateral CDI and lateral cartilage volume (manual segmentation) in this test dataset (lateral femur: spearman correlation = 0.74; lateral tibia: spearman correlation = 0.77; lateral tibiofemoral: r = 0.80, all p < 0.0001).
However, we found a good correlation between baseline lateral CDI and lateral cartilage volume (manual segmentation) in our test dataset (r = 0.74 to 0.80, p < 0.0001).
The reliability set was selected based on baseline lateral JSN grade (5 knees per lateral JSN grade).
While we only used 18 informative locations, our baseline lateral tibiofemoral CDI had a better correlation with lateral JSW (r = 0.81, p < 0.0001).
All measurements were performed with the subject in the left lateral position at baseline, during 5% carbon dioxide inhalation, and during a 2-minute isometric handgrip test.
Tests for trend were used to examine associations of lateral CDI with baseline JSN and KL grade.
Vertebral fractures were adjudicated from baseline lateral lumbar and thoracic spine radiographs based upon a previously developed protocol [ 28].
