We demonstrate, using a guinea pig model of I. scapularis feeding and B. burgdorferi transmission, that immunity directed against salivary proteins expressed in the first 24 h of tick attachment — and not later — is sufficient to evoke all the hallmarks of acquired tick-immunity, to thwart tick feeding and also to impair Borrelia transmission.
While IIS pathway knockdown starting on the first day of adulthood or even later is sufficient to extend lifespan, mitochondrial genes have to be knocked down during larval stages for increased longevity (Dillin et al., 2002).
Important evidence concerning two of the piracy cases was suppressed at the trial, and some observers later questioned whether the evidence was sufficient for a guilty verdict.
Sharansky would not have been surprised to learn that Kennan also felt "fairly at home" in Berlin in the years before America's entry into World War II, and "regretted" our involvement in the war (though he later wrote that the Holocaust was sufficient reason to fight Germany).
Thus, the 12 ns measurement time during the later half of 24 ns simulation was sufficient for monitoring the dynamics of contacts, We also observed transient formation of β-sheets, consistent with experiment.
In another case, individual screening was triggered, and NAT was done, but before the screening results were received, a granulocyte unit was released for transfusion use; testing results later showed that the WNV load was sufficient for detection by NAT of pooled and individual blood samples (16 ).
Lord Buckmaster explained the reasoning in the House of Lords two years later: "It is sufficient to say that the reason why the speed limit was abolished was not that anybody thought the abolition would tend to the greater security of foot passengers, but that the existing speed limit was so universally disobeyed that its maintenance brought the law into contempt".
According to a paper published in Science, in Chesapeake Bay (where we know more about the original nature of the ecosystem, as large-scale exploitation began later) there were sufficient oysters to have "filtered the equivalent of the entire water column every three days".
The onsets of Pi2 waves at stations between OSAK and RABB (THRF and BRDN) are later; there are sufficient data in this part of the plot that we may have confidence in the contours as drawn.
Wnt10b knockdown was sufficient to induce 24 hours later SREBP-1c protein expression in myoblasts.
