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A later study demonstrated that the YTE variant had 10-fold increased binding to human and cynomolgus FcRn at pH 6.0, which translated into a 4-fold increase in half-life in a cynomolgus PK study (Dall'Acqua et al., 2006).
Interestingly, the later study demonstrated that prevascularization of the chamber was not required when syngeneic islets were seeded with NGF.
A later study demonstrated that Tfr cells could suppress both activation and proliferation of responder T cells and IgG production in vitro [ 55].
The later study demonstrated that the low [Cl−]i upregulated p21 (a CDK inhibitor), implying that inhibition of CDK2 and Rb was caused by the upregulated p21 57.
Although a later study demonstrated that no physical interaction of both enzymes in vitro is necessary in order to yield cis-OPDA [ 48], it appeared highly questionable to us if cis-OPDA can be formed by the action of spatially separated PpAOC1/2 and PpAOS1.
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Early studies suggested that the frontal error ERPs corresponded only to valence of outcomes [24, 28, 29], while later studies demonstrated that both valence and magnitude of outcomes influenced FN signals [15, 30, 31, 32].
Later studies demonstrated that the H9N2 subtype might have allowed the HP H5N1 subtype to persist and circulate in poultry.
Later studies demonstrated that LFBs not only differ from HFPs in terms of their firing rate and pattern, but also in their modulation by the state of the animal.
However, later studies demonstrated that phosphorylation of P-glycoprotein did not influence its function [ 26, 27].
Later studies demonstrated that daily administration was equally tolerated and was as effective as administration on alternate days [ 53, 56].
Later studies demonstrated that this association is critical for the rapid expression of early G1 genes upon exiting mitosis [ 47– 50].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com