Then a conceptual characterization of a given phenomena which was used at an earlier stage may not be at a later stage as, for instance, the judgment 'A light-ray consists of a stream of moving particles', drawn from Newtonian optics was later replaced by 'A light-ray consists of electromagnetic waves'.
These experiments thus do not clarify the role of acute autophagy loss at a later developmental stage, for instance in an established tumour, a scenario that likely occurs in vivo.
Whether STAT3 activation is also necessary at later stages in RGC regeneration, for instance to maintain the regenerative state as previously shown for mTOR activity, could not be addressed in our study.
Deloitte, for instance, has called for the later stage funding gap to be filled by the financial community and for entrepreneurs themselves to step up to invest in and develop these companies.
In addition, it is one of the few censures in which a bishop was involved right from the start, and not, for instance, at a later stage of the proceedings as judge of an appeal.
Some hypothesize that the lack of isolated bacteria from long-term high antibody level cattle is due to a latent infection stage that can later be reactivated, for instance during stress around calving or due to transportation.
All genes of the JA biosynthesis are either down-regulated or up-regulated at later stages in susceptible plants, as for instance expression of LOX (T0 -8.66; T1 1; T2 2) increases only at T1.
For instance, low-grade prosthetic joint infections, presenting as pain and loosening of the implant at a later stage, will generally be missed in surveillance programs for surgical site infection.
Hence, in those instances in which bacterial motility may be required for efficient colonization of tissues, induction of the injectisomes should be triggered at a later stage.
For instance, the expression of lamprey EmxB at early embryonic stages is expanded more ventrally than that of mouse Emx2 [ 10], and the onset of FGF signaling in lamprey forebrain occurs at a later stage than in mice [ 42- 44].
