Exact(2)
For an updated discussion on early and later specifications of this concept, see Holopainen, Toivonen [18].
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It remains to be determined how the M. occidentalis ASMPs migrate to the general vicinity of the future atrial siphon opening and remain localized there until the later specification and differentiation of the siphon.
In mutant embryos, we could not observe alterations neither in the onset of retinal neurogenesis (characterized by sonic hedgehog expression [ Shkumatava et al., 2004]) nor in the later specification of RGCs or other retinal cell types.
With this system, it will be necessary to search for the molecular mechanisms sustaining the "instructive potential" of the epithelium, as required for the specification of mesenchymal cells, the initiation of odontogenesis and later, the specification of a dental epithelial-mesenchymal junction.
While Pedroni [31, 32] test was carried out by using the later deterministic specification, 4 statistic have found to be significant when panel cointegration was checked with infant mortality while the number was 6 if it was tested with life expectancy.
When Dex was added later during specification (stages 15 and 18) a greater percentage of the embryos (84% and 79%, respectively) showed an expanded kidney field (Fig. 2E 2H, 2M).
Despite the existence of large amount of data concerning the mechanisms patterning the early endomesoderm segregation, little is known about the regulatory landscape of the later NSM specification.
In contrast to its role in liver specification, an inhibitory role for Wnt/β-catenin signaling in anterior endoderm pattering, whose proper pattering is prerequisite for later liver specification, has been reported in other systems.
South Africa's air force chiefs selected an Italian aircraft that is cheap and modern, but the politicians later amended the specifications to favour the ageing British Hawks, twice the price of the Italian tender.
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