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The studies described above suggest that in some tumor types pRb inactivation results in both a loss of cell cycle control, which promotes initial tumor growth, as well as in a loss of cell-to-cell contacts, which later contributes to metastasis.

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The explanation is that shape probabilities add up from many small contributions, and there is no way to determine early which subshapes may later contribute to the top-ranking ones.

He later contributed to Fox News.

(Mr. Nathanson later contributed to this version of the script).

He left NASA in 1986 and later contributed to books about Skylab and physics.

He later contributed to magazines, studied the Kennedy assassination and pursued an interest in sailing.

Mr. Burdick later contributed to the liner notes for the boxed set, which is to be released on Sept. 29.

In 1776 the British, who controlled New York City, arrested Salomon; exposure suffered in prison later contributed to his early death.

Spa development after 1626 and sea bathing later contributed to Scarborough's burgeoning as a fashionable 18th-century resort.

In the 1990s, he produced a Flash Gordon series for Marvel and later contributed to the Sunday strip.

"If we are talking about peace and mutual understanding, it means investing in people who will later contribute to Palestinian society," he said.

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