One long-held hypothesis, he says, is that early infection creates a latent vulnerability to schizophrenia that is only "unmasked" by later insults, such as physical injury or psychological trauma.
This study provides a better understanding of the widely held view of the multi-dimensional domains of frailty and its concept as a latent vulnerability in older people.
Mindfulness-Based Cognitive Therapy (MBCT; Segal, Williams, & Teasdale, 2002) is a treatment programme that was specifically designed to address latent vulnerability in depression.
This mirrors the concept of frailty as a latent vulnerability in older adults, subtle, often asymptomatic and only evident over time when excess vulnerability to stressors reduces the older person's ability to maintain or regain their homeostasis[ 26].
Insomnia symptoms are thought to precipitate poor mental health under a diathesis-stress model [ 43] where the stress and opportunities for negative rumination associated with long, wakeful nights facilitate expression of a latent vulnerability to psychopathology [ 16, 41].
In addition, we assessed whether O3 exposure increases latent vulnerability to cardiac arrhythmia, hypothesizing that O3 acts through the autonomic nervous system to prime the heart to react to secondary challenges.
Inclusion of a stressor task in this type of research is also important given diathesis-stress conceptualisations that propose negative cognitive biases are latent vulnerability factors that only directly influence symptoms once activated by a disorder-relevant stressor [ 11].
The latent variable of vulnerability included observed variables, such as the involvement of vulnerable cases, and drug and genetic studies.
Diathesis refers to the latent weakness or vulnerability that that a child or adult may carry (e.g., difficult temperament, particular gene), but which does not manifest itself, thereby undermining well-being, unless the individual is exposed to conditions of risk or stress.
The latent variables of vulnerability and PIs interacted with review and acted as moderators of approval.
