Additionlly, the induction of lytic genes may also be committed to a small population of the infected cells that eventually dies but are critical for induction of the proliferative genes and switching to a latent type infection.
We found that, indeed, MCF was associated predominantly with a latent type of viral gene expression and, furthermore, we may have detected an important clue to understand and, possibly, treat MCF in the future.
The latent type of persistent infection is typical for BDV.
In immunocompetent individuals CMV infections are of chronic or latent type and are usually not associated with clinically detectable disease.
EBV latent type II antigens, including latent membrane protein-1 and protein-2 (LMP1 and LMP2) and EBV nuclear antigen 1 (EBNare, are present in ENKL tumor cells.
Ophthalmic examination disclosed a manifest nystagmus of the latent type, i.e. a rapid jerk nystagmus beating leftward in both eyes.
Host cells with the lytic type of EBV infection, but not the latent type, express virally encoded kinases that can phosphorylate the prodrug, GCV, and convert it to its active cytotoxic form.
The observed connectivity between two cells R(e i, e j ) then depends only on their latent type and their distance through a link function f(⋅, d(e i, e j )).
In contrast, the latent type III EBV antigens, including EBNA1-6, LMP1 and LMP2, and BARFO, are presented by EBV-infected cells in post-transplantation lymphopro-liferative disorder (PTLD) [10], [11].
