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Although some global features of S. cerevisiae replication are conserved: Centromeres replicate early, whereas telomeres replicate late, we found that replication origins both in L. kluyveri and L. waltii do not behave as evolutionary fragile sites.
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Importantly, we find that late neutralization of IL-12 interrupts the downregulation of CXCR3 expression on late-stage effector tgd057-specific CD8+ T cells.
We find that late school entry by one year reduces the incidence of juvenile crime for young black females, particularly in high crime areas.
In addition to the multivesicular organization, we find that late endosomes contain cholesterol rich microdomains both on their limiting membrane and their intraluminal vesicles that differ in composition and properties.
When directly comparing VMAT-treated patients with 3DCRT-treated patients in terms of tumor response, acute and late toxicity we found that VMAT provides equal tumor regression combined with reduced acute and late organ toxicity.
By following rats from birth to late senescence, we found that rats that experienced 3-min daily exposures to a novel environment for the first 3 weeks of life exhibited greater ability to win in social competition than their siblings that stayed in the home cage and, remarkably, that this enhanced competitive success was detectable during old age.
Using the starting numbers of 66 "early" and 65 "late" miRNAs, we found that this procedure mapped 31 and 45 miRNAs, with 549 and 531 target mRNAs, respectively.
At late telophase, we found that the posterior but not the anterior centrosomes elongated along the anteroposterior axis with its posterior end reaching to the posterior cortex (Fig. 1a; 2:40, Fig. 1b,c; 2:00).
When we analyzed co-localization between CD63 and LC3 as a sign of fusion between autophagosomes and late endosomes/lysosomes, we found that in MLIV patient cells 68.8% (SD ± 11) of the LC3-positive vesicles co-localize with CD63 after 20 min recovery, and this percentage increased to 87.7% (SD ± 7) after 40 min (Fig. 6).
By examining dominant and subordinate females from queen and worker castes in early and late season colonies, we found that cuticular hydrocarbon profiles and genome-wide patterns of brain gene expression were primarily associated with season/social environment rather than dominance status.
By mapping the location of five Z chromosome genes and the late replication locus, we found that the terminal region of short and long arms were switched between Zsm and Zm, leaving the locations of SPIN (spindlin), GHR (growth hormone receptor), and DMRT1 the same (Fig. 4).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com