Feelings about this matter exist on a huge spectrum, but I think this admittedly late step toward advancing people's civil rights is a wonderful thing.
Cyclic AMP regulates the late step of Ca2+-dependent exocytosis in many secretory cells through two major mechanisms: a protein kinase A-dependent and a cAMP-GEF/Epac-dependent pathway.
The dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase functions in a late step of the pathway and converts N-succinyl-l,l-diaminopimelic acid to l,l-diaminopimelic acid and succinate.
The practice of estimation is associated with uncertainties, due to the determination of the power consumption in a late step of the design technique, or just simply has a low reliability.
Rps15p was shown to be involved in nuclear export, a late step in ribosome biogenesis [6].
This finding suggests that TRAF6 regulates the late step of mature B cell development or homeostasis.
We propose DNA methylation as a late step in epigenetic silencing because 5-aza-dC treatment did not affect the initiation of silencing.
Thus, we conclude that the ESCRT system is not required for the assembly of infectious particles but the ESCRT system is required for late step of HCV production.
Since celastrol did not inhibit substrate cleavage by LF, this result indicated that this compound might block a late step in intoxication.
This suggests that the ESCRT system plays a role in the late step after the Core is targeted into lipid droplets in the HCV life cycle.
Promoter DNA methylation is the most common modification associated with epigenetic silencing, and has previously been thought to play a causal role [9], but evidence is accumulating to suggest DNA methylation as a late step in the silencing process.
