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Many firms face yawning gaps in their pipelines of drugs at a late stage of development.
But there has been a very high failure rate, often at a late stage of development, when companies have spent a great deal of money – in some cases as much as $300m – on research and development.
In the Japanese trial the scientists found that about 30% of infertile men lacking fully formed sperm or immature sperm at a late stage of development possessed round spermatids.
The ossification of most skeletal elements11, as well as the histology of a similarly sized embryo, MOR 246-133, from the same clutch indicate that this embryo (MOR 246-11) was in a late stage of development and close to hatching.
This time-dependent phenotype may reflect the synaptic maintenance function of MECP2 at late stage of development.
However, in the late stage of development, a conventional geological model is not able to meet the needs of production in the oilfield in that the reservoir architecture has been the main factor influencing the distribution of remaining oil.
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Currently, only a few stroke drugs are in the late stages of development.
These plants expressed pga2 only at late stages of development, and their growth was comparable to that of WT plants.
With the purchase, SFBC will expand PharmaNet's labs and acquire its line of research for drugs in the late stages of development.
The fund is also planning to spend money on a final push to bring to market vaccines in the late stages of development, including one for viral diarrhea.
For example, a new treatment for breast cancer now in the late stages of development drew on work that scientists in the agrochemical division had carried out on antifungal agents.
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