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However, we continue to be a major tenant at Discovery Park and have around 700 research and development colleagues based at the site, working on Pfizer's mid to late stage development pipeline and developing medicines for clinical trials in a wide range of disease areas including cancer and diabetes".
The problem is that with what is late stage development work, it is not fundamental 'new' science so is very unlikely to be sent to a peer reviewed publication.
Gatifloxacin has provided an example of multiple form changes throughout mid to late stage development.
Adding usability improving solutions during late stage development is to some extent restricted by the software architecture.
It is thus imperative that compounds brought forward do not fail in late stage development and the two features that have a major impact are pharmacokinetics and toxicity.
Novel serogroup B meningococcal vaccines are currently in late stage development and may be used in mass immunisation campaigns over the coming years.
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While the APOE4 allele was identified as a significant risk allele for late-onset AD in the early 1990s, to date there are no late- stage development programs targeting this pathological mechanism.
Lilly's drugs in late-stage development include potential treatments for cancer, multiple sclerosis, diabetes and Alzheimer's disease.
More recently, the company has pointed to signs of improvement in its late-stage development program, citing 18 new molecular entities in its pipeline.
Witty said the drug maker had received positive data for five products in late-stage development to treat HIV, cancer, diabetes and asthma.
Sanofi-Aventis, which makes Ambien and its long-acting formula, Ambien CR, has another sleeping pill in late-stage development, eplivanserin.
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