Sentence examples for late onset condition from inspiring English sources

'Patients without symptoms' (Finkler et al. 2003) include those 'at risk' of developing a late onset condition (in the case of Huntington disease for example) and carriers of a genetic disorder (in the case of recessive disorders such as cystic fibrosis or X-linked disorders such as haemophilia).

In each of these diseases, a particular protein slowly becomes converted into amyloid, giving rise to the typical late onset condition.

However, with the dearth of research exploring patient responses to mitochondrial disease, useful comparisons can be drawn with other late onset conditions such as Huntington's Disease, where the profound social and emotional effects are better explored (Richards 2004) and where the uptake of presymptomatic testing is low (Evers-Kiebooms et al. 2002).

The timing of some late onset conditions may exceed the lifespan of hiPSC-derivatives in culture, and innovative strategies are required.

And many people who would not have an abortion for a late-onset condition would find embryo selection acceptable.

Given that PKD is a late-onset condition that progresses at a moderate rate in pc mutants, the medaka pc mutant has a relatively long life when compared with zebrafish pronephric models of cystic kidney, such as vHnf1, double bubble, and oval (polaris/IFT88/osm-5) mutants [16] [23].

Decisional privacy and the requirements of autonomy are also at issue in the debate over the legitimacy of parental consent for the genetic testing of minors for late-onset conditions (Clayton 1997b; Cohen 1998; Sevick et al. 2005).

Predictive genetic testing may be done for late-onset conditions for which a patient is not yet symptomatic.

Early-onset conditions are defined as disorders with clinical symptoms that begin in infancy or childhood, whereas late-onset conditions appear in adolescence or adulthood.

The definition may also include personal utility for life planning, encompassing return of information on predispositions to untreatable late-onset conditions.

16 This pattern has been consistently observed in populations affected by Huntington disease 17 18 which has been considered a model of understanding the attitudes towards (predictive) testing for late-onset conditions with no treatment or cure 19 such as many inherited retinal diseases.