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An early exposure within the first weeks showed a negative impact on bone regeneration in contrast to a late exposure [12, 23 25].
It is also noteworthy that the relatively late exposure of Inner Lesser Himalayan rocks predicted by the structural model would have served to input significant amounts of relatively low εNd material into the basin after 5.4 Ma.
Historically, the derivation of peripheral nervous system (PNS) cell types from mouse and primate ESCs has relied on co-culture with the mouse stromal line PA6 and late exposure to BMP4 [12] or, in the case of hESCs, co-culture with PA6 [13].
Finally, the aox operon was induced after late exposure.
No such induction was observed in late exposure.
Indeed, after late exposure, phosphate specific transporter (Pst) and phosphate inorganic transporter (Pit) were induced.
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Seven children developed diabetes, including four in the late-exposure group.
In the late-exposure group, four children had a biopsy and all had celiac disease.
Seven children developed diabetes (three in the control group and four in the late-exposure group).
An additional eight children developed islet autoantibodies after the age of 3 years (five children in the late-exposure group).
The development of height and weight during the first 3 years of life did not differ between the control and late-exposure groups (Fig. 3 B ). Weight gain during the first year of life (control group: 5,630 g vs. late-exposure group: 5,640 g; P = 0.6) and from age 12 to 48 months (control group: 7,070 g vs. late-exposure group 7,230 g; P = 0.9) was comparable between groups.
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