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The late defects showed different complementation behaviours than the defects in ventral furrow formation.
The defects we observe at successive stages of gastrulation could be the result of the failure of different genes, each acting at a different stage, or the late defects could be due to the early failure in ventral furrow formation.
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Another mutation which is epistatic to Lula for sensitivity to DNA damage is uvrD, a late defect in the UvrA-initiated nucleotide excision repair (Fig. 5D) [28].
hecd-1 (ok1437 ) also enhances a different egg-laying problem associated with reduced lin-12 activity, the "late defect" (Sundaram and Greenwald 1993).
The late defect has a complex basis including aberrations in uterine and sex muscle development (Eimer et al. 2002; Newman et al. 1995); we did not characterize the cellular basis of this enhancement further.
On sample ZnO, A1 LO) mode at 590 cm−1 has the higher intensity that can be attributed to Zni and not to VO as the sample was dry milled, and oxygen atoms at the surface limit formation of these latest defects.
Clostridium tyrobutyricum is an anaerobic bacterium responsible for late blowing defects during cheese ripening and it is of scientific interest for biological hydrogen production.
Feeding dried distillers grains with solubles (DDGS) to lactating dairy cows has been implicated as a cause of late blowing defects in the production of Swiss-style cheeses.
Then, by analyzing pure neuronal cultures from DAP12KI pupsups, we investigated the impact of the prenatal period in inducing late synaptic defects.
We focused our screen on mutations specifically causing late onset defects, since this is a typical characteristic of neurodegenerative diseases [44].
We assume that each of the deficiency stocks may have accumulated independent background mutations elsewhere in the genome, which, perhaps in conjunction with the delay in the formation of the ventral furrow, lead to late gastrulation defects.
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