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Second, we propose that an anti-ageing approach could be more successful in early than late ageing stages; middle-aged people seem to be the most appropriate candidates.
The decrease of compressive strength of geopolymer at late ageing stage can be correlated to the phase transition.
This approach was chosen to minimise the possible bias due to the stochastic effects of late ageing.
In this way, we focused exclusively on the late ageing, in which the effects of ageing are directly linked with increased mortality rates.
Thus, the small but statistically significant decline in cancer incidence in late ageing individuals may be the product of decreased regenerative rates and stem cell numbers.
These time-points were chosen because they represent terminal differentiation and early and late ageing, respectively, based on various criteria discussed in the introduction (see also Supporting Information Fig S1).
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