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It becomes therefore important to know the time to first spike, which would be a measure of the speed of gamma phase resetting, as well as the time to last spike and the spiking frequency during excitable period.
The last spike was bad enough.
One other observation: obviously, people who bought gold at the peak of the last spike got badly burned.
And fervent nationalists see the proposed merger as the loss of a revered national symbol and the last spike in the dream of an independent, sovereign Canada.
A pyramidal monument marks the spot where the golden (last) spike was driven on May 10 , 1869 linking the Central Pacific and Union Pacific railroads.
Pratt's next work, Towards the Last Spike (1952), is a narrative of the building of the Canadian Pacific Railway (1870 85).
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Spike delay analysis was performed by aligning the last spikes before light stimulation in each trace for each cell and measuring the time to the next spike after light stimulation; the measurements were normalized to the cell's average ISI.
In the region excited by the weaker stimulation, the peak Δ[Ca2+]i increased with the stronger stimulation (Figure 2B), but the peaks of ΔVm corresponding to the last spikes did not change (Figure 2C).
Additionally, our data showed that the first spikes in eSWR show the strongest reverse-order activation tendency, while the last spikes of a spike train show no such tendency at all.
Similar to the analysis using the first SWR spikes, we selected median spikes (e.g. the second spike if a cell fired three times) and the last spikes during SWRs, and measured how these SWR spike-times correlated with times of the last pre-SWR action potentials.
Drivers like Tival Williams, 39, a self-employed fashion designer from the Ditmas Park area of Brooklyn, also learned from the last price spike.
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