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Fifteen of the 26 patients (58%) who experienced an isolated local recurrence are alive, and 12 of those patients (46%) are disease free with a median follow-up time of 22 (range 4 57) months after the last recurrence.
A thorough cytologic evaluation of corneal scrapings was found to be of great help in these cases, but comprehensive sampling is crucial as indicated by positive findings in only one out of several slides at the last recurrence in case 1. Listerial infections are commonly treated with penicillins or tetracylines, which may be effective in early stages of systemic disease.
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Disease-free survival (DFS) was calculated from the date of definitive surgery until last contact; recurrence 'local, regional, or distant'; occurrence of contralateral breast cancer; occurrence of second primary cancer other than in the contralateral breast; or death without evidence of breast or second primary cancer.
Do I date remission at the last chemotherapy session, recurrence at the start of the next chemotherapy cycle?
Via telephone the treating gynecologist was asked about the time of the last examination, possible recurrences and therapies of the patient.
She is doing well without recurrence until last follow-up at 15 months after operation.
Among the patients cured 1 week after the last application, the mycological recurrence rate after 1 month was significantly higher in the econazole group (32.7 vs. 19.8%, P=0.035).
If the event occurs uniformly and randomly, the probability of an event does not depend on the elapsed time since the last event, and the recurrence interval between successive events is distributed exponentially.
Further indications include assessment of post-treatment response, long-term surveillance to detect recurrence and, last but not least, detection of an unknown primary tumour [1, 2, 3, 4, 5].
Blues also have long-term concerns about Jonathan Spector, who is out for an estimated three months with a recurrence of last season's thigh injury, and left-back David Murphy's knee.
Three injections of autologous fat grafts harvested by the Coleman's technique were realized and few months after the last one, a local recurrence of osteosarcoma occurred 13 years after the initial treatment.
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