In contrast, preclinical antiviral evaluations require groups of animals sufficiently large to demonstrate statistical proof of efficacy in vivo.
However, the sample size was sufficiently large to demonstrate a statistical correlation between the classical prognostic variables of tumour size, lymph node status, lympho-vascular invasion, metastases and the NPI.
Surprisingly, compliance was not associated with socioeconomic status, suggesting either that the number of participants was insufficiently large to demonstrate an effect, or that the principal impact of socioeconomic status is on participation.
With locally advanced disease treated by aggressive combined modality in most of our subjects, we found that the dosimetric improvement for 3DCRT compared with IMRT might not be sufficiently large to demonstrate any significant difference in HR-QoL.
The largest group to demonstrate inside the free speech zone was made up of about 100 opponents of the Israeli occupation of the West Bank.
Our study is the largest study to demonstrate urinary AGT/Cr as a useful clinical parameter associated with renal dysfunction and underlying pathophysiology.
This is the largest study to demonstrate elevated COX-2 expression in pure DCIS and has shown COX-2 overexpression in both in situ and IBC compared with normal breast.
Eight studies report a negative survival association with CRM+ on multivariate analysis, whereas seven others, including the two largest, failed to demonstrate an independent survival association with CRM status.
While not all compounds and bioactivities stored in PubChem today were considered in this study, the data set employed is large enough to demonstrate that the large-scale clustering of small molecules in PubChem is possible.
Students took to the streets, often in strikingly large numbers, to demonstrate against postsecondary tuition increases.
