"largest responsibility" is correct and usable in written English.
You could use it in a sentence like this: "I take my largest responsibility as a parent very seriously."
And the S.E.C., which has the largest responsibility under Dodd-Frank, alone has missed 53 deadlines, according to Davis Polk.
The S.E.C., which has the largest responsibility under Dodd-Frank, alone has missed 54 deadlines, according to Davis Polk.
Who wants to marry a guy whose largest responsibility is asking customers whether they prefer the Glass or the Bread?
She believes Israel carries the largest responsibility for the current crisis enveloping Gaza, but adds that the Palestinians in the West Bank and Gaza also carry a share of the burden, as does the rest of the Arab world for its silence.
It's a larger and larger responsibility that needs to be taken very seriously".
But did they also consider their larger responsibility to American interests?
A ballerina, whether arrogant or humble about it, must show the larger responsibility that says, "Le ballet, c'est moi".
"Hamburg has a large responsibility for Sept. 11, nationally and internationally," said Walter Wellinghausen, Hamburg's deputy interior minister.
The U.S. bears a large responsibility for many of the things that have gone wrong in Pakistan.
So let's remember that universities themselves bear a large responsibility in "keeping college affordable for all Americans".
"They were supposed to be honest brokers, but instead, they put their own financial interests ahead of that larger responsibility".
