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But a critical evaluation by Australian researchers in a recent British Medical Journal article concludes that the authors of the largest published studies "have exaggerated the benefits, downplayed the harms, or both," possibly because of financial ties to the pharmaceutical industry.
Our data also shows clearly that the highly-cited study [23] that concluded that "Five of the seven largest published studies addressing cancer prognosis did not classify patients better than chance" reached these conclusions because of two main reasons: first, the specific null hypothesis tested was inappropriate and second, because several underpowered analysis components were employed.
Table 2 shows a summary of the largest published studies.
This is one of the largest published studies in a commercially insured population to examine the association between compliance with palivizumab and RSV-related hospitalizations.
To our knowledge, this is one of the largest published studies of population-based estimates of dietary supplement use and their relationship to usual blood pressure.
Though our study is one of the largest published studies on combined effects of the germline genetic variation and tumor somatic events, the numbers are still small for looking at such modifying effects on survival.
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This study is also the largest published study of the effect of influenza on military communities.
This contrasts with laparoscopic radiofrequency ablation of fibroids, in which the largest published study to date reported a median time for returning to normal activities of 9 days (range, 2 60 days) [31].
In this, the largest published study regarding the accuracy of staging of rectal cancer with the primary objective of assessing the depth of tumour extension in rectal cancer, T4-staging was done accurately in only five out of 14 cases [14].
To our knowledge, this is the largest published study on CTCs with mature outcome data.
In the largest published study, the fatality rate was 2.8% (7 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com