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The goal is to gain the largest possible level of structural, treatment-related and observational similarity between test and control groups through randomisation and blinding, with a subsequent evaluation following the "intention to treat" (ITT) principle [ 1- 3].
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Compared with other statistical methods, uniform design (UD) reduces the number of experiments in a multiple-dimension optimization and allows the largest possible number of levels for each factor (Yan and Bogle 2007).
But, unlike orthogonal design, the largest possible amount of levels for each factor can be allowed in Uniform Design, and so much so that the number of levels sometimes can be equal to the number of experiment runs [ 24].
On the cautious side, even in the extreme cases of 7 1 allele ratios at the DNA levels, twice the largest possible allele ratio at the DNA level should be 14 1.
In order to guarantee a good quality, the halftoning algorithm should be able to represent the largest possible number of intensity levels with a minimum number of bits.
We identified SNPs with combined allele ratio of greater than 14 (twice the largest possible allele ratio at the DNA level) as being allele-specifically expressed.
For instance, if two families are used as in this study, at an SNP site, the largest possible allele ratio at the DNA level is 7 1, i.e., AA x AG in one family, and AA x AA in the second family, where the largest possible allele ratio at the DNA level is 7A 1G.
In contrast, random process parameter effects are associated with those parameters whose levels are randomly chosen from a large population of possible levels.
Most of these studies that compare health expenditures on the international level try to work with the largest possible aggregates of costs [ 7, 12].
Equations (29)–(43) is a bi-level max min problem for identifying the largest possible security violation.
Second, in many countries, the obtained coverage data are relatively high because they reflect the minimum possible level of afforded legal protection to the largest possible base of workers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com