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However, the largest positively charged surface included the polymerization region, which spanned the cofactor binding domain, as observed in ALDH families 6, 7 and 10 (Figures S5D, S6D, and 7D) and to a lesser degree in the other families.
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The leucine104 is located only 4 Å from glutamic acid 334; replacing it by a large, positively charged arginine would alter the position of site II.
The result is several large, positively geotropic roots that produce higher-order roots, which may also grow to the same size.
Each vanadate tetrahedron has a net charge of -3, which is neutralized by large, positively charged metal ions (e.g., calcium, manganese, or ferrous iron) outside the tetrahedron.
Each arsenate tetrahedron has a net electric charge of -3, which is neutralized by large, positively charged metal ions (e.g., calcium, manganese, or ferrous iron) outside the tetrahedron.
The importance of interaction between MCM-41 and safranin (a large positively charged dye) was examined in a previous study [15].
(H) The Docking DNA/MrkH complex structure, in the proposed MrkH dimer two separate DNA-binding regions merge into a larger positively charged area binding DNA.
The active site of GALNS is a large, positively charged trench suitable for binding polyanionic substrates such as keratan sulfate and chondroitin-6-sulfate.
According to their research, "the implementation of combined policy measures to improve the quality of both the P&R facility and the connecting public transport and to discourage car drivers to use their car for door-to-door trips have large, positively effects on the use of the P&R alternative" [5].
It involves a conservative exchange of one large, positively charged residue (histidine) for another (arginine).
The rs28943580 SNP results in the exchange of a large positively charged residue, arginine (R), for a smaller polar residue, cysteine (C) with a thiol group.
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