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The reduction is size dependent and affects even the largest investigated target structures with volumes of about 500 mL.
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Our study is population-based and the largest investigating the relation between ESR1 and endometrial cancer to date.
Noteworthy, our series is the largest investigating the proliferation rate measured with Ki-67 immunostaining and its impact on outcome in SFTP.
The study sample is one of the largest ever investigated in TMS studies and the largest sample of patients with chronic tinnitus.
Using purified disaccharide products of B4GAT1 or LARGE, we investigated B4GAT1 and LARGE for potential branching activity.
Of these, the six largest were investigated in more detail.
The most consistent sequences obtained came from the largest fragment investigated (see Additional File 2).
Eight-six patients with cancer, 168 subjects with benign conditions of the stomach and large bowel and 720 individuals from the community at large were investigated.
Recently, two larger studies investigated the relation between dietary phylloquinone and insulin sensitivity.
No large study investigated the interest of using hydroxyethylstrach (HES) for fluid loading in ARDS patients.
One large EWAS investigated the association between DNA methylation in cord blood and maternal smoking (Joubert et al. 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com