The Lasker Foundation declined to comment, other than to note that Dr. Tu's citation mentioned that Project 523 was a large collaborative effort.
The current study was the result of a large collaborative effort of CUMC and other medical centers in the US, Italy, Poland, Croatia, Macedonia, and the Czech Republic.
The canine clinical trial program is part of a large collaborative effort, coordinated by Richards, to accelerate the development of therapeutics.
In a large collaborative effort with 26 other laboratories worldwide, the Morimoto lab helped identify a small molecule called celastrol, from a plant often used for its anti-inflammatory properties in Chinese herbal medicine.
The Cherenkov Telescope Array (CTA) is a large collaborative effort aimed at the design and operation of an observatory dedicated to the very high-energy gamma-ray astrophysics in the energy range 30 GeV 100 TeV, which will improve by about one order of magnitude the sensitivity with respect to the current major arrays (H.E.S.S., MAGIC, and VERITAS).
The data aggregators used here include many different sources of information and researchers that have participated in this large collaborative effort.
It remains to be tested whether missense mutation carriers will display features similar to truncating mutations, but this will presumably require a large collaborative effort given the paucity of known pathogenic missense mutations.
They are capable of making many different neural cell types and were the source of cells for a large collaborative effort to model Huntington's disease using iPSCs (21).
Reference databases of transcript profiles have been algorithmically mined to identify transcript patterns in treated animal tissue that predict pathology seen only with more extensive treatment [ 22, 23], and a large collaborative effort has confirmed the validity of this approach [ 24].
The International HapMap Project is a large collaborative effort that has made publicly available genotype data for 270 individuals from four different populations: Yoruba in Ibadan, Nigeria (YRI); Japanese in Tokyo, Japan (JPT); Han Chinese in Beijing (CHB), China and Utahh residents with ancestry from northern and western Europe (CEU) [ 2].
