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In particular, larger rod- and disk-shaped PEG NPs show more uptake than smaller ones, opposite to the size effect observed for spherical particles in a flow.
The contrast of the larger rod diameters (5 mm, 4 mm, 3 mm, and 2 mm) is already close to its maximum value (>95%) after iteration 1 and therefore at image noise values as low as 5%.
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AgNO3 showed immediate toxicity, whereas the small spherical nanoparticles showed the rapid development of toxicity followed by toxicity equilibrium and the larger rod-shaped nanomaterials became toxic more slowly but toxicity was still increasing at the end of the test.
After doping LPCS, the results of inverted microscope (IM) and atomic force microscopy (AFM) illustrated that the immobilized gel beads changed from rod-like in shape with a smooth surface to a larger rod-like ultrastructure with a rougher surface.
Larger rods (1800 × 400 nm) are observed to adhere at least 3 times more than smaller ones (1500 × 200 nm).
This needs to be compensated with high density fuel (uranium nitride), larger rods and mainly higher enrichment.
While the steric effect for spheres causes larger spheres to elute faster than predicted by normal mode theory, an inverse steric effect occurs for rods in which larger rods move increasingly slower than predicted by theory.
The difference in site density of the ligand for spherical nanoparticles when compared to the platelet and rod samples may be due to a difference in the packing of the ligand on a highly curved surface such as the small spherical nanoparticles, when compared to the packing of the ligand on more planar surfaces like the platelets or the larger rods.
In contrast, the larger, rod-like structure in Nesonektris has a more constant width, is only present in the posterior body region and never extends beyond the distal end of that region.
These findings also introduce the possibility that changes in collagen I microstructure (as measured by SHG) may alter collagen I's ability to form larger rod-like fibers, thus altering the relative proportions of "diffuse" versus "large fiber" collagen I (and TACS patterning) in WT versus MMP13 KO mice.
Due to their small size and symmetric shape, charge separation is very limited for these particles, as evidenced by Figure 5 a: they have a larger overlap integral with respect to the larger rod-shaped samples #7 and #8 (due to their smaller size) but smaller overlap integral with respect to samples #1 and #2 since they are type-II.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com