Sentence examples for larger rationale from inspiring English sources

"With respect to the larger rationale of public safety, if what they're trying to do is identify people with criminal records, it makes no sense to simply target the immigrant population," Budd said.

The larger rationale, of course, is that same-sex marriage is much too toxic politically for him — even now — and that if the President wants to be President next year he has to stay away.

Since Arabs and Muslims are so passionate about the Palestine problem, this argument runs, the Israeli-Palestinian stalemate feeds regional anger and despair, gives a larger rationale to terrorist groups like Al Qaeda and to the insurgency in Iraq and obstructs the formation of a regional coalition that will help block Iran's quest for nuclear weapons.

When attacked, Obama's responses have always been couched in the larger rationale for his candidacy.

The larger ambition, a basic rationale for the deal, is the one that is most in doubt, even among supporters of the Compaq merger.

The effects observed in our cohort provide the rationale for larger studies in independent cohorts to validate the results presented here.

These findings establish the rationale for larger validation studies in early breast cancer to evaluate ctDNA as a monitoring tool for early metastasis detection, therapy modification, and to aid in avoidance of overtreatment.

Our results in the context of prior studies provide a strong rationale for larger trials that are adequately powered for smaller effects on urine albumin excretion or trials that are conducted in participants who take ACE/ARB therapy.

Given the increasing availability of novel immunomodulatory agents, combination studies with sipuleucel-T are warranted; augmentation of the immune parameters described herein would provide a strong rationale for larger studies to demonstrate increased clinical efficacy.

In conclusion, the addition of a weekly low dose of tamoxifen did not impair anastrozole bioavailability and favorably modulated its safety profile, providing the rationale for larger studies of this combination treatment.

The rationale, in large part, has been to distribute more of the production costs for EADS products, which are priced in dollars, outside the euro zone and reduce the group's exposure to fluctuations in the foreign-exchange rate.