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The much larger protective effect of 9R/9R after the ages of 15 16 is not accidental; it can be explained by the legal driving age of 16 in the United States.
Consequently, we might then have seen a larger protective effect of aspirin, as the incompletion was higher among users of aspirin.
The stratification of these studies, for example, has revealed that citrus fruit consumption was associated with a larger protective effect against oral cancer than overall fruit consumption, and was greater than green- or overall vegetable consumption [ 6].
It is known that chemoprophylaxis against tuberculosis disease has a larger protective effect in HIV-infected individuals who are TST positive than it does in HIV-infected individuals who are TST negative (27).
Other risk factors are specific to the risk of trauma during a fall, and correction of these factors by exercise may also help explain the larger protective effect of exercise on serious injuries such as fractures.
Thus, meta-analyses of alcohol consumption and the risk of ischemic heart disease (Roerecke and Rehm 2012) and ischemic stroke (Taylor et al. 2009) found a larger protective effect for morbidity than for mortality related to these conditions.
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Interestingly, our preliminary data regarding transgenic overexpression of DNAJB6 indicate even larger protective effects in the R6/2 mice (our unpublished results).
14 15 16 This hypothesis is supported by our analyses, in which former drinkers commonly exhibited increased hazards before multivariate adjustment, with models compared with pooled non-drinkers portraying larger protective effects across a wider range of use than never drinkers only (tables 1-4).
However, the wide confidence intervals were consistent with a large protective effect, no effect, or a large adverse effect.
Nevertheless, the trial does suggest a potentially large protective effect that was consistent throughout the follow-up period, and robust in sensitivity analysis.
Furthermore a large protective effect of maternal education (beyond elementary level) was found in a Mexican population (OR 0.6 (95% CI 0.5; 0,8)) [ 44].
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