The amount of the functional glycans was undetectable in the lysates from the Lec15.2-LG cells with the IIH6 antibodies, while its Large expression level is compatible to that in the other CHO-LG cell lines (Fig. 1A).
The resulting, smoothed threshold fold-difference envelope was then applied to the two compound-treated/control array pairs to identify those probe-sets that have large expression level differences between treatment and control.
The WEE1 gene harbours a large expression level in the pCR group.
For total protein expression levels there are large expression level differences observed between the various C-terminal tags.
This intermediate expression could make it more difficult to detect expression differences, while the large expression level changes in the NV-C severe group make it easy to detect them against NV-NC control.
Larger burst sizes would predict larger maximal expression levels, or conversely measurements of absolute expression levels might give suggestions about the burst size for translation in the early Drosophila embryo.
Even though the two tumours may differ in their microenvironmental characteristics, the large differences in uptake patterns have been primarily attributed to the tracer targeting capability since SKOV-3 has substantially larger HER2 expression levels than A431.
This selection approach will tend to favor genes with larger absolute expression levels, and a diverse range of expression values across the samples.
A model with two states is chosen via BIC (Additional file 1: Figure A1) and the state with larger gene expression levels on average has the weaker association with histone methylation levels (Additional file 1: Table A2 and Figure A2).
Also in agreement with the replication patterns is that large chromosome expression levels appear to gradually decrease with an increased distance from the origin of replication, which is also supported by ori/ter ratios larger than 1.
