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Moreover, unlike conventional acute phase proteins that are largely synthesized in the liver, HSP10 and HSP60 are found in every cell as nuclear encoded genes which function within the mitochondria.
Ser and Gly were largely synthesized via the glyoxylate (GOC) cycle followed by photorespiratory reactions [ 26].
Thus, it is unlikely Ser was synthesized solely from route 1, route 2 or route 4. It is more likely that Ser was largely synthesized, as in higher plants [ 34], from Gly via the photorespiratory pathway (route 3).
ABA, a key regulator of seed maturation and embryogenesis, is largely synthesized in the integuments and its level in seeds is high during mid- and late-maturation stages (reviewed by [ 35]).
As suggested by Murray and Wolf reptile plasma incorporation rates are likely similar to those of other ectotherms (Murray and Wolf, 2012) because plasma proteins are largely synthesized in the liver which have a similar function in most organisms (Tieszen et al., 1983).
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This section largely synthesizes existing work, but is lucidly presented and provides a platform for more detailed discussions, in the latter half of the book, of individual philosophers and overarching trends.
The PPAR α in active UC was synthesized largely by epithelial cells, monocytes/macrophages, and lymphocytes, but not for adipose tissue.
Caspases are first synthesized as largely inactive zymogens known as procaspases and are later activated through posttranslational mechanisms.
Although the pathways through which AcCoA is synthesized are largely species-dependent, we could demonstrate that the nucleo-cytosolic pool was more important for repressing autophagy than the mitochondrial pool, both in yeast and in mammals (Fig. 1).
Although CD4+ T cell help for antibody responses to some viral antigens may be minimal, these antigens differ from PsaA-BLyS in that they are primarily endogenously synthesized and largely presented on MHC class I.
While causality is difficult to demonstrate due to the largely observational nature of data synthesized in reviews, evidence suggests that engaging in volunteering activities may provide beneficial social, physical, and cognitive outcomes for older people [ 23- 32].
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