Recently various drug candidates with excellent anticancer potency have been demonstrated, whereas their clinical application largely suffers from several limitations especially poor solubility.
It also survived the 2008 recession largely intact, though suffered from high inflation in the past couple of years.
At the time of the Reformation, it became largely Protestant and suffered from persecution after the revocation in 1685 of the Edict of Nantes, which had accorded a measure of religious liberty to Protestants in 1598.
The neighborhood was largely ignored and suffered from crime and gang violence.
In 2008, a resuscitation effort built largely around retail offerings suffered from the recession and from inexperience -- Disney inexplicably reassigned the Muppets to an events team responsible for organizing movie premieres.
Senator Jack Reed, a Rhode Island Democrat who was in the 82nd Airborne Division, told reporters on Tuesday by telephone that the Iraqi security forces still suffered from largely untested leaders, unproven loyalty to the government and fledgling ministries that were struggling to build the institutional support to sustain the troops in the field.
Theories surrounding her image change largely rumoured that she had suffered from an eating disorder.
Avellino is largely modern, for it has suffered from numerous earthquakes in its history, the most recent in 1980.
But after you've had 10 seconds you'll never forget, it becomes a narcotic". Mr. Steiger, who suffered from depression, was largely sidelined in the 1980s but determinedly sought out acting parts in recent years.
In hindsight, however, it suffered from being a largely passive consumption experience, and from its isolation from the context of Twitter's broader conversations.
