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This is in line with our previous observation that GR-mediated activities in the context of EAE are largely refined to the peripheral immune system and only indirectly impact on CNS infiltration [19].
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This analysis complements and largely refines previous analyses performed on a much smaller number of genomes (Abrouk et al. 2010) or done separately within monocots and dicots (Salse et al. 2008, 2009b; Murat et al. 2010).
Our previous data and associated conclusions that largely refine the public animal paleogenomics data (detailed previously) can now be considered in the context of published studies that discussed consequent impact sexual chromosomes on the reported WDG pattern.
Therefore, our data confirm and largely refine previous conclusions suggesting LRR as a 'glue' for domain association leading to new combinations of R-gene domains observed in modern species, one major source of R-gene plasticity.
The requirements of Oxfam and the other relief agencies have largely been refined over the last decade, in the light of hard won experience from a stream of emergencies.
Exports, which consist largely of partly refined nickel and nickel ore, vary with the world market price of nickel.
3 Though self-learning via access to published material is of undoubted importance, medicine is an apprenticeship and knowledge is largely obtained and refined through discussion with colleagues; both seniors and peers.
Reports have suggested it will be similar to OS X Snow Leopard, which was largely meant to refine the experience of OS X Leopard.
After this antimony-containing secondary lead is refined, it is largely resold to battery manufacturers.
His brand of accessible, refined observational humor largely defined 1980s comedy, but he is no longer as influential.
In the final quarter, manufacturing output fell by 0.6%, driven largely by falls in metals, refined petroleum, chemical and pharmaceutical products and food and tobacco.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com