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Maintenance of a single ARS1-containing plasmid was largely perturbed at the restrictive temperature in orc5-1 mutants, but rescued by the presence of multiple ARSs.
For example, in the phosphate buffer, Na 2SO 4 is suddenly able to significantly perturb Trp9, Asp23 and Asn25, which are not largely perturbed by Na 2SO 4 alone in water either at pH 6.4 or 4.0.
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A similar dilemma exists when planning components of management, termed "renoprotection," to prevent in diabetic patients onset and treat progression in renal disease that has been largely attributed to hypertension induced by a perturbed renin-angiotensin-aldosterone system.
These contacts are largely conserved in AF4 family members and can be perturbed physically and functionally by mutations.
However, these perturbed isotopic distributions are mostly correct.
The perturbed hand quickly adapted to the large initial errors.
I remain a little perturbed.
Others are just plain perturbed.
You may be confused, or perturbed.
"Don't get perturbed," he said.
In fact, I am just perturbed and confused.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com