Sentence examples for largely on sequence from inspiring English sources

These serpins have been divided into 9 clades of related proteins, based largely on sequence homology [ 1].

A robust diagnosis of sequence variation in the vicinity of the target SNPs will depend largely on sequence coverage, sequence quality [ 34] and origin of sequences as far as the number and relatedness of individuals surveyed for SNP discovery.

Here, we follow the principle of current common practice and base our considerations largely on sequencing of Illumina libraries of different lengths (we loosely refer to short reads at sequence lengths below 500 bp and long reads above this length).

A: Right now our diagnostics is largely based on sequence data from Sierra Leone.

This is mostly due to the extensive heterogeneity of AGEs created by glycation reactions: Glycation reactions are not largely dependent on sequence specificity, and lysine and arginine residues, which are particularly susceptible to glycation, are very common in proteins.

Besides, the power of SD analysis depends largely on genomic sequence and its annotation.

Dalrymple and colleagues [ 15] constructed a virtual map of the sheep genome based largely on end sequencing of the CHORI-243 BAC library used in this study, including structural comparisons and synteny with the better characterised genomes of other mammals.

B-1a cells express all of these detected VH genes, contrasting with earlier impressions, based largely on hybridomas sequences from fetal and neonatal mice (Malynn et al., 1990), that VH usage in the B-1a repertoire is very restricted.

The data presented herein describe the first published analyses of echinoderm splice sites and suggest that the previous methods of identifying splice signals that are based largely on vertebrate sequences may be insufficient.

In addition, the degree of gene coverage is largely dependent on sequencing depth and complexity of the communities.

The reduced-taxa data set was largely based on sequences used in other studies [ 31, 56], complemented by additional sequences for crucial species (see Additional file 1, Table S1).